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Effects of supplemental mycotoxin deactivator on lactation performance of Holstein cows fed natural mixed mycotoxin contaminated feed.

N. L. Whitehouse

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06-24-2020

324
Effects of supplemental mycotoxin deactivator on lactation performance of Holstein cows fed natural mixed mycotoxin contaminated feed.
N. L. Whitehouse*1, H. C. Robertson1, B. K. Kerns1, S. M. Hollister1, L. H. P. Silva1, S. M. Fredin2. 1University of New Hampshire Durham, NH, 2Adisseo USA Inc Alpharetta, GA.

Mycotoxin contamination of feed ingredients poses a serious health risk to dairy cows. The objectives of this trial were to determine the effects of a mycotoxin deactivator on lactation performance and plasma leukocytes in dairy cows fed mixed mycotoxin contaminated feed. Twenty-four Holstein cows (147 ± 58 DIM) were used in a replicated randomized block trial for 7 wks. Treatments were 1) negative control diet (NC); 2) positive control diet with mycotoxin exposure from contaminated dried distillers grains (PC); and 3) PC diet plus 30 g/d of mycotoxin deactivator (UNIKE Plus, Adisseo; UP). Milk yield and DMI was determined daily, averaged by wk. Milk samples were collected on the last 3 d of each wk. Blood samples were collected from the coccygeal vein for 3 consecutive d at the end of the covariate wk and wk 3 and 6 for analysis run on the veterinary hematology platform. Data were analyzed using the MIXED procedure of SAS with REPEATED measurements. Significant effects were noted at P ≤ 0.05. The TMR in the PC diets increased zearalenone from 290 to 683 µg/kg and deoxynivalenol from 2,013 to 4,772 µg/kg compared with NC diet. Intake decreased for cows fed PC compared with NC but improved for cows fed UP, whereas ECM yield was decreased for cows fed PC compared with NC but unaffected for cows fed UP. Cows fed PC and UP had elevated SCS compared with NC. Leukocytes were unaffected by treatment, but monocytes were elevated for cows fed NC and UP compared with PC. Adding a mycotoxin deactivator improved DMI and ECM yield, increase monocytes with no affect on the other immune cells for cows fed natural mixed mycotoxin contaminated feed.Table 1. Effects of mycotoxin contamination and deactivation on cow performance

ItemNCPCUPP-value
TreatmentWeekTreatment × Week
DMI, kg/d25.323.324.10.090.0010.02
Milk yield, kg/d41.640.740.90.800.0010.04
ECM, kg/d40.539.240.10.620.0010.008
SCS1.3b1.8a1.8a0.010.070.23
Neutrophils, cells/μL4,5434,1254,7390.070.0020.82
Lymphocytes, cells/μL3,3162,8713,3380.690.830.98
Monocytes, cells/μL351a272b368a0.010.030.80
Leukocytes, K/μL8.57.68.70.260.350.98
a,bMeans within rows differ for Trt (P < 0.05).

Keywords: leukocytes, mycotoxin.